A review by Krueger 2 found that studies on the behavioral implications of sleep deprivation in humans repeatedly showed increased reaction times, decreased accuracy, decreased attention, and negative alterations in mood. Fatigue induced by sustained wakefulness can cause slower reaction times, a reduced ability to multi task, and increases in lapses of attention that can lead to costly, even deadly mistakes 1. In general, it is a serious public health risk.
CtVNS could be a powerful fatigue countermeasure tool that is easy to administer, long-lasting, and has fewer side-effects compared to common pharmacological interventions.įatigue is a serious and unavoidable problem for many professions such as medicine, transportation, and the military. The ctVNS group performed significantly better on arousal, multi-tasking, and reported significantly lower fatigue ratings compared to sham for the duration of the study. Two groups (active or sham stimulation) of twenty participants in each group completed 34 h of sustained wakefulness. The objective of this research was to evaluate the efficacy of cervical transcutaneous vagal nerve stimulation (ctVNS) to mitigate the negative effects of fatigue on cognition and mood. It is reasonable to suspect that other types of non-invasive neuromodulation may be similarly effective or perhaps even superior. These can be effective in limited circumstances but other non-pharmacological fatigue countermeasures such as non-invasive electrical neuromodulation have shown promise. Common fatigue countermeasures include caffeine or other chemical stimulants.
Fatigue is a pervasive public health and safety issue.
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